I heart LOST: Trivia

Hurley uses the numbers 4, 8, 15, 16, 23, and 42 to win the lottery. During the season 1 finale, as Hurley drives to the airport, the numbers appear on the dashboard as the car stalls. Running to the gate, he passes a girl's soccer team with the same numbers on their uniform jerseys. They also appear on the hatch exterior and the vial Desmond uses for injection.

4, 8, 15, 16, 23, 42 all added together equal 108, the total of minutes left to enter those very numbers into the computer